Bees can help us treat cancer. More specifically, their venom, which effectively kills breast cancer cells.
This conclusion was made by Dr. Ciara Duffy in the course of her research at the Harry Perkins Institute of Medical Research in Perth. Their results have just been published in the journal Nature Precision Oncology.
Bee venom versus breast cancer
Dr. Duffy hopes the discovery will lead to the development of a treatment for triple-negative breast cancer, which accounts for 10 to 15 percent. all cases of breast cancer and for whom there are currently no clinically effective targeted therapies.
`` We've found that honeybee venom is extremely effective at killing some of these really aggressive breast cancer cells. And at concentrations that are not as harmful to normal cells, says Dr. Duffy.
Research has shown that appropriately selected concentration of bee venom kills 100 percent. triple negative breast cancer cells
And HER2-enriched breast cancer cells within 60 minutes with minimal effect on normal cells.
The venom itself came from the honeybee hives at the University of Western Australia, as well as from Ireland and England. The bees were anesthetized with carbon dioxide and kept on ice before the venom was extracted and injected into the tumors. The key component of the venom, acting on cancer cells, turned out to be melittin.
"Melittin actually penetrates the surface or plasma membrane of cancer cells and creates holes or pores in it, simply causing cell death," says Dr. Duffy.
An additional action of melittin is to block the reproductive signals in cancer cells and HER2. The substance also enhances the effect of drugs used in chemotherapy. All thanks to the formation of breaks in the membranes of cancer cells, thanks to which the traditionally used drugs are able to penetrate them and act with greater force.
This is not a breakthrough yet
At least this is what the author of the study says, who emphasizes that more research is needed on the effect of melittin on cancer cells. Professor Peter Klinken, one of the reviewers of the Duffy study, said that this was another great example of the use of naturally occurring compounds to treat human disease.
The next step Duffy wants to take is to thoroughly test the toxicity and the maximum dose of melittin that can be tolerated by the human body. Another issue is the synthetic process of melittin formation, thanks to which scientists would not have to rely on bees.
Don't miss out on new texts. Follow Spider's Web on Google News .
Bee venom is effective in killing cancer cells. It will help in the fight against breast cancer
معلومات مفيدة للغاية شاركتها هنا حول تمر الصقعي . هذه طريقة رائعة لتعزيز المعرفة بالنسبة لنا ، كما أنها مفيدة لنا. شكرا لتقاسم مثل هذا المقال.
ReplyDelete