There is a mutation that will completely resist our pain

Imagine a world where stepping on a Lego brick is painless, and the occupation of an anesthetist is limited only to putting patients to sleep before surgery. Sounds too good to be true?

For Mrs. Jo Cameron, 71-year-olds from Scotland, that's how it works . Thanks to the tiny, random defect in her DNA chain, she does not feel any pain. She is informed by her sense of smell about the burns she has received, and she only learns about open wounds when she sees the blood.

She was surprised by her doctors, very surprised by the fact that the patient refuses any painkillers after the surgery. Nothing hurt her, so why?

A bit of code responsible for pain

Unfortunately, our body is constructed in such a way that it is in vain to look for a single center responsible for experiencing pain. In fact, it is a whole network of very complicated connections, which sometimes even happen completely against logic.

For example, in cases phantom pain, i.e. feeling pain in a part of the body that we lost for some reason (eg a hand resulting from amputation). Therefore, many doctors devote their entire lives to understanding the mechanisms responsible for the fact that we feel this unpleasant feeling.

Of course Jo Cameron never experienced it. Somewhere, in the jungle of complicated protein chains that make up her DNA, there is apparently no key fragment, thanks to which all her pain-sensing centers remain inactive.

Imagine a potentiometer knob that symbolizes the scale of pain sensation. Let's say that the average person has them set at some 6. The hypersensitive dangerously approaching 11 (fans of the movie This is Spinal Tap will understand), some lucky oscillates around 4, and Mrs. Cameron goes through life set to equal zero.

Interestingly, this missing piece (or a few pieces) of its DNA code also causes all wounds sustained by it to heal much faster than the average human. And, in conversations with doctors excited about the properties of someone else's body , an elderly lady from Scotland said she had never suffered from anxiety, depression and other related symptoms - I know that it is very, very generalizing - with mental pain. Does it have anything to do with her bizarre mutation? This is not known yet. Perhaps.

Scientists, of course, want to replicate this disadvantage

... and create new, wonderful analgesics on its basis.

Pharmaceutical companies have been chasing after this Holy Grail, which is 100%. effective analgesic. Jo Cameron is unique with his absolute lack of pain, but that does not mean that he is the only person with whom his feeling has been reduced. Research departments of pharmacological concerns know such, a little less extreme cases and for years have been trying to develop chemical blockers that would be able to reduce the sensation of pain in the same way.

However, this is not the optimal solution. A much better idea would be to analyze Mrs. Jo Cameron's DNA, discover the missing, modified piece of her DNA code responsible for the absolute lack of pain and ... repeat this trick on someone else's DNA, thanks to the CRISPR / Cas9 gene editing method.

The method itself remains as yet underdeveloped and scientists warn that it is not accurate enough to be editable for the human genome, but it's only a matter of time. We already know what needs to be done, we only wait to improve the tools that would enable us to do so. Piece of cake.

How to use such a discovery?

A new wonderful world in which no one is afraid of dentists is just one side of the coin. The second is genetically modified soldiers, not experiencing pain. Do you think I am being carried away by fantasies drawn straight from sci-fi movies? No. I am quoting the report on the US national security of 2016, in which its author, James Clapper, director of the National Intelligence Agency, calls the technology of gene editing another weapon of mass destruction.

For now, this is of course quite a distant prospect, but with the current pace of development of science, sooner or later private clinics will offer such modifications. The potential that is slumbering in improving our DNA is too large for us to ignore.

Of course, we are first waiting for endless discussions on the ethics of such solutions, but - as is usually the case with our species - the desire for potential profits and pure curiosity will eventually win. Most people have already got used to GM foods.

So why not start to modify people? Who would not want to be immune to HIV, completely not feel pain or wake up fully rested after just a few hours of sleep? And this is just the tip of the top of the possibilities that we offer to modify our own source code.



There is a mutation that will completely resist our pain

Comments

Popular posts from this blog

What is VoLTE and how can you activate it on your Xiaomi

So you can check the battery status of your Xiaomi smartphone and how many cycles you have performed

How to exit the FASTBOOT mode of your Xiaomi if you have entered accidentally

Does your Xiaomi charge slowly or intermittently? So you can fix it

Problems with Android Auto and your Xiaomi? So you can fix it

If your Xiaomi disconnects only from the WiFi it may be because of that MIUI setting

How to change the font in MIUI and thus further customize your Xiaomi: so you can change the type, color and size of the letters of MIUI

What is the Safe Mode of your Xiaomi, what is it for and how can you activate it

Improve and amplify the volume of your Xiaomi and / or headphones with these simple adjustments

How to activate the second space if your Xiaomi does not have this option